Ectomesenchymal chondromyxoid tumor (ECMT) is a rare tumor, exclusively arising in the anterior tongue. Thirty-eight cases have been reported in the English literature. It usually presents as a sessile protrusion and shows round to spindle cells embedded in myxoid to chondroid stroma. Tumor cells are almost always positive for polyclonal glial fibrillary acidic protein (GFAP). We report our experience in the recent treatment of a case of ECMT, the third case in 3 years. The mass in the anterior tongue revealed characteristic morphologic features of ECMT and the expression of polyclonal GFAP. Although ECMT should be differentiated from other mesenchymal tumors including myoepithelioma, its clinical, morphological, and immunohistochemical features enable its diagnosis, especially when pathologists are aware of it.

Citations

Citations to this article as recorded by  

• Ectomesenchymal chondromyxoid tumor of the oral cavity: a report of 5 new cases with comprehensive review of the literature and clinicohistopathologic features
  Molly Housley Smith, Jack Moynihan
  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.2023; 135(3): 410.     CrossRef
• Chondroid choristoma of the tongue: A rare case report
  Sumaiya Nezam, Roquaiya Nishat, ShababAhmed Khan, JeevendraNath Shukla
  National Journal of Maxillofacial Surgery.2022; 13(4): 121.     CrossRef
• Ectomesenchymal chondromyxoid tumor: a comprehensive updated review of the literature and case report
  Astrid Truschnegg, Stephan Acham, Lumnije Kqiku, Norbert Jakse, Alfred Beham
  International Journal of Oral Science.2018;[Epub]     CrossRef
• Clinical features of ectomesenchymal chondromyxoid tumors: A systematic review of the literature
  Masanari G. Kato, Evren Erkul, Kendall S. Brewer, Emily E. Harruff, Shaun A. Nguyen, Terry A. Day
  Oral Oncology.2017; 67: 192.     CrossRef
• Cyclin D1 Expression in Ectomesenchymal Chondromyxoid Tumor of the Anterior Tongue
  Jan Laco, Radovan Mottl, Walter Höbling, Stephan Ihrler, Petr Grossmann, Alena Skalova, Ales Ryska
  International Journal of Surgical Pathology.2016; 24(7): 586.     CrossRef
• Nodular lesion in the buccal mucosa
  Bruna Jalfim Maraschin, Ana Carolina Amorim Pellicioli, Lélia Batista de Souza, Pantelis Varvaki Rados, Marco Antonio Trevizani Martins, Manoela Domingues Martins
  The Journal of the American Dental Association.2015; 146(3): 196.     CrossRef